Prednisone | The Basics

Written by mike on . Posted in Prednisone and Cortisone Information

What is prednisone?

This is a common question asked by many people who are prescribed Prednisone or other corticosteroids. Prednisone is a man-made hormone commonly known as a “steroid.” Prednisone is essentially the same as hormonal cortisone, which the human body creates on its own.

Its effects are comparable to other corticosteroids, such as methylprednisolone (Medrol), triamcinolone (Kenacort), dexamethasone (Decadron) and prednisolone (Prelone). These unnatural corticosteroids simulate the effect of cortisol (hydrocortisone), a naturally-transpiring corticosteroid produced in the human body by the adrenal glands. Corticosteroids have several effects on the human body, but in most cases are utilized for their powerful anti-inflammatory effects, specifically in those ailments in which the body’s defense mechanism plays a vital role. Such conditions incorporate joint disease, colitis, asthma, bronchitis, several skin breakouts, and inflammatory or allergic issues of the eyes and nose. Prednisone is sedentary in the human body and as a way to be useful; it must be transformed first into prednisolone by digestive support enzymes in the liver. For that reason, prednisone may not act as efficiently in people who have liver problems, whose ability to transform prednisone to prednisolone is damaged.

“What is prednisone used to treat?” Prednisone is helpful for treating inflammatory problems or illnesses in which the immunity mechanism plays a major role. In some conditions, the immune system generates antibodies that turn out to be overactive and result in undesirable effects. These ailments are known as “autoimmune illnesses.” Prednisone suppresses the creation of antibodies. This suppression makes it slightly harder for a sufferer to protect against infection, and also balances the immunity mechanism if it is over-active. As prednisone is commonly used to treat many ailments, only the most frequent or proven uses are outlined here.

As mentioned above, prednisone in most cases is used for curing several types of joint diseases, ulcerative colitis, Crohn’s disease, systemic lupus, hypersensitivity, symptoms of asthma and intense skin psoriasis. It is also used for treating leukemias, idiopathic thrombocytopenic purpura, lymphomas and autoimmune hemolytic anemia. Adrenal cortical steroids, which include prednisone, are generally used to control the immune system and hinder the human body from rejecting replanted organs. Prednisone can be used as an alternative therapy in sufferers whose adrenal glands find it difficult to produce adequate amounts of cortisol.

The initial dosage of prednisone differs according to the illness being cured and the patient’s age. The starting dosage may be from five to sixty milligrams per day and is often adjusted depending on the effect of the ailment being cured. Corticosteroids normally do not result in quick effects and should be used for many days before best possible effects are achieved. It may take considerably longer before conditions respond to the treatment. When prednisone is finished after a time of prolonged treatment, the dosage must be tapered gradually, to enable the adrenal glands for recovery. Sufferers should continue to take Predni-Vite or other supplements designed to help with the continued side effects.

Sufferers taking prednisone should be on low salt diets and try to eat well-balanced foods. When starting prednisone, there is a possibility that it may result in serious increased susceptibility of infection for a short period of time, so users need to be aware of this seek medical attention if necessary.

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